Human Prostate Gene DataBase

 Database Statistics 
 

PGDB (v.1.1);  Nov 30, 2002 

What's new in this update:

  • Included genes involved in the molecular event of apoptosis in the prostate.
  • Included more prostate-specific genes derived from SAGE and EST expression analysis. In Version 1.0, for gene or ESTs to be included the the database, they must express exclusively in the prostate and have at least 5 member EST or SAGE tags derived from prostate libraries. In this update, this number was lowered to 2. 
  • More annotations were added to each gene such as Reference Sequence from GenBank, links to Ensembl and UCSC genome map

Statistic Data

1. Literature Coverage

   January 1st, 1970 - Nov 30, 2002

2. Total number of non-redundant genes and references in PGDB.

Genes

References

527

518

3. Number of genes and supporting references by category in PGDB. 

Category

Number of genes

Supporting references

Category by molecular event

 

 

 

Amplification

 

 

 

 

Prostate cancer

16

45

  Apoptosis    
    BPH 2 2
    Prostate cancer 58 136
    Normal prostate 1 1

 

Mutation  

 

 

 

 

BPH*

3

5

 

 

Prostate cancer

49

190

 

Gross deletion

 

 

 

 

Prostate cancer

24

32

 

Methylation

 

 

 

 

BPH

1

2

 

 

Prostate cancer

27

69

 

Polymorphism

 

 

 

 

BPH

3

3

 

 

Prostate cancer

28

94

 

 

Prostatitis

3

3

 

Over expression

 

 

 

 

Normal prostate

3

3

 

 

Prostate cancer

11

12

 

Linkage

      Prostate cancer

Misc. Events**

 

 

5

23

 

 

Normal prostate

3

2

 

 

Prostate cancer

11

10

Category by expression

 

 

 

Prostate specific gene by EST

285

-

 

Prostate specific gene by SAGE

62

-

 

 

 

* Begin prostatic hypertrophy; ** Prostate related genes as identified by other methods such as data mining

4. Number of references by year and by molecular or genetic event.


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Programming: Long-Cheng Li
2002-2004, PGDB, All Rights Reserved.
Dahiya's Urology Research Center
Department of Urology
VA Medical Center and University of California, San Francisco