| Name | kallikrein 3, (prostate specific antigen) |
| Symbol | KLK3 |
| Aliases | APS; PSA; antigen, prostate specific |
| Gene Product | - kallikrein 3, (prostate specific antigen)
|
| Category | - Polymorphism in Prostate cancer
|
| UniGene | Hs.171995 |
| OMIM | 176820 |
| Locus | 354 |
| Summary | Prostate-specific antigen; kallikrein 3 serine protease |
| Gene Ontology | |
| Expression | | EST (856 ESTs, 81 libraries) |
| Tissue ? |
Frequency ? |
Count ? |
| blood (1/27) |  | 10/40686 |
| colon (2/853) | | 2/165626 |
| head and neck (1/990) | | 1/79796 |
| liver (1/38) | | 1/46472 |
| lung (2/312) | | 3/245386 |
| muscle (1/21) | | 4/71297 |
| nervous (1/475) | | 4/43438 |
| placenta (3/342) | | 4/157762 |
| prostate (59/291) |  | 592/109871 |
| uncharacterized tissue (9/1773) | | 234/713325 |
| uterus (1/212) | | 1/155110 |
|
| SAGE (11520036 tags, 230 libraries) |
| Tissue ? |
Frequency ? |
Count ? |
| blood (1/1) | | 4/97046 |
| brain (14/19) | | 33/1775309 |
| cerebellum (1/1) | | 2/102560 |
| colon (6/8) | | 12/677282 |
| eye (4/6) | | 13/871692 |
| heart (1/1) | | 1/84357 |
| kidney (2/2) | | 2/73935 |
| liver (1/1) | | 2/133722 |
| lung (1/1) | | 1/89143 |
| mammary gland (9/19) | | 13/553045 |
| ovary (4/10) | | 6/243113 |
| pancreas (5/8) | | 11/363137 |
| prostate (12/13) | | 1137/4250132 |
| skin (2/7) | | 2/31317 |
| stomach (3/3) | | 13/298232 |
| uncharacterized tissue (16/22) | | 326/1607670 |
| vascular (2/3) | | 5/268344 |
|
|
| SNP | rs2003783 (G/T:coding-nonsyn); rs12101 (C/T:mrna-utr); rs174776 (T/C:intron); rs2569735 (A/G:locus-region); rs1058205 (T/C:mrna-utr); rs2292185 (G/T:intron); rs266875 (G/A:locus-region); rs1053980 (C/T:intron); rs1053972 (C/T:intron); rs2053087 (A/G:intron); rs12040 (A/G:mrna-utr); rs1803129 (T/C:mrna-utr); rs2271092 (A/G:intron); rs12863 (A/G:mrna-utr); rs762549 (C/G:intron); rs1058274 (A/G:mrna-utr); rs2739449 (C/G:coding-nonsyn); rs2659120 (G/A:intron); rs266859 (G/A:locus-region); rs1810020 (C/T:intron); rs6998 (G/A:mrna-utr); rs1061476 (T/C:intron); rs1802720 (T/C:mrna-utr); |
| Evidence | Polymorphism in Prostate cancer
|
