| Name | death-associated protein kinase 1 |
| Symbol | DAPK1 |
| Aliases | DAPK |
| Gene Product | - death-associated protein kinase 1
|
| Category | - Methylation in Prostate cancer
|
| UniGene | Hs.153924 |
| OMIM | 600831 |
| Locus | 1612 |
| Summary | Death-associated protein kinase 1 is a positive mediator of gamma-interferon induced programmed cell death. DAPK1 encodes a structurally unique 160-kD calmodulin dependent serine-threonine kinase that carries 8 ankyrin repeats and 2 putative P-loop consensus sites. It is a tumor suppressor candidate. |
| Gene Ontology | |
| Expression | | EST (157 ESTs, 85 libraries) |
| Tissue ? |
Frequency ? |
Count ? |
| blood (2/27) |  | 2/40686 |
| bone (1/13) | | 1/26211 |
| brain (9/204) | | 21/362011 |
| connective tissue (1/1) | | 1/1301 |
| embryo (1/19) | | 1/37976 |
| eye (5/33) | | 6/93836 |
| germ cell (1/7) | | 5/57383 |
| heart (1/22) | | 3/55494 |
| intestine (1/4) | | 1/11528 |
| kidney (2/86) | | 2/132968 |
| liver (1/38) | | 1/46472 |
| lung (5/312) | | 13/245386 |
| muscle (2/21) | | 6/71297 |
| nervous (2/475) | | 2/43438 |
| ovary (2/144) | | 3/81880 |
| pancreas (4/33) | | 6/117255 |
| parathyroid (1/4) | | 3/19377 |
| placenta (16/342) | | 34/157762 |
| skin (2/31) | | 2/100815 |
| stomach (2/312) | | 4/129930 |
| testis (1/171) | | 1/117531 |
| uncharacterized tissue (18/1773) | | 32/713325 |
| uterus (4/212) | | 6/155110 |
|
| SAGE (5498126 tags, 102 libraries) |
| Tissue ? |
Frequency ? |
Count ? |
| blood (1/1) | | 3/48523 |
| brain (14/19) | | 17/900087 |
| colon (3/8) | | 5/233459 |
| eye (6/6) | | 8/453737 |
| heart (1/1) | | 1/84357 |
| kidney (1/2) | | 1/41857 |
| liver (1/1) | | 1/66861 |
| lung (1/1) | | 3/178286 |
| mammary gland (7/19) | | 9/496340 |
| ovary (4/10) | | 5/175415 |
| pancreas (4/8) | | 9/337619 |
| prostate (5/13) |  | 16/573581 |
| skin (1/7) | | 1/22466 |
| stomach (2/3) | | 8/404994 |
| uncharacterized tissue (11/22) | | 34/1136032 |
| vascular (2/3) | | 6/344512 |
|
|
| SNP | rs729958 (C/T:intron); rs1861827 (C/T:mrna-utr); rs943854 (A/G:intron); rs2149377 (G/T:intron); rs1887792 (A/G:intron); rs1064221 (T/G:mrna-utr); rs2068771 (G/A:mrna-utr); rs1804417 (G/A:mrna-utr); rs3128524 (A/G:mrna-utr); rs1927978 (C/T:intron); rs877861 (C/T:intron); rs2270404 (G/C:mrna-utr); rs2378753 (C/T:intron); rs1927973 (A/G:mrna-utr); rs1468928 (A/T:mrna-utr); rs3095753 (C/T:mrna-utr); rs1007394 (C/T:intron); rs3118873 (A/G:intron); rs3031545 (-/CA:intron); rs2889980 (A/C:intron); rs2225211 (A/G:mrna-utr); rs1024883 (C/T:mrna-utr); rs1056719 (G/A:coding-nonsyn); rs2183026 (G/T:intron); rs2282012 (A/C:intron); rs2042006 (C/G:mrna-utr); rs3124238 (C/T:mrna-utr); rs888338 (C/T:mrna-utr); rs1421000 (A/G:mrna-utr); rs1015477 (A/C:mrna-utr); rs3118841 (C/T:mrna-utr); rs1410577 (C/T:intron); rs2111554 (T/C:mrna-utr); rs1558892 (C/T:mrna-utr); rs884605 (A/G:mrna-utr); rs2209914 (T/C:intron); rs3118870 (T/C:intron); rs2274601 (G/C:mrna-utr); rs3128470 (A/C:intron); rs3118867 (A/G:mrna-utr); rs721936 (A/G:intron); rs1005090 (C/T:intron); |
| Evidence | Methylation in Prostate cancer
|
