Human

Human Prostate Gene DataBase

Name solute carrier family 2 (facilitated glucose transporter), member 2
Symbol SLC2A2
Aliases GLUT2
Gene Product
  • solute carrier family 2 (facilitated glucose transporter), member 2
Category
  • Amplification in Prostate cancer
UniGeneHs.167584
OMIM138160
Locus6514
SummaryGlucose transporter 2 isoform is an integral plasma membrane glycoprotein of the liver, islet beta cells, intestine, and kidney epithelium. It mediates facilitated bidirectional glucose transport. Because of its low affinity for glucose, it has been suggested as a glucose sensor.
Gene Ontology
Expression
EST (56 ESTs, 13 libraries)
Tissue ? Frequency ? Count ?
kidney (2/86)0.321 6/132968
liver (2/38)0.986 19/46472
lung (1/312)0.176 1/245386
muscle (1/21)0.225 1/71297
spleen (1/7)1.000 2/9511
uncharacterized tissue (6/1773)0.539 27/713325
SAGE (3061722 tags, 57 libraries)
Tissue ? Frequency ? Count ?
blood (1/1)0.039 1/48523
brain (3/19)0.246 4/225516
cerebellum (1/1)0.670 3/102560
colon (5/8)0.144 6/316302
eye (3/6)0.102 4/315003
heart (1/1)0.136 1/84357
kidney (1/2)0.137 1/41857
liver (1/1)1.000 12/267444
lung (1/1)0.129 1/89143
mammary gland (4/19)0.208 6/359446
ovary (7/10)0.743 8/254151
pancreas (3/8)0.229 3/95504
prostate (4/13)0.177 5/270044
skin (1/7)0.330 1/11563
stomach (2/3)0.462 8/277331
uncharacterized tissue (5/22)0.226 7/244974
vascular (1/3)0.198 1/58004
SNPrs2859841 (G/T:intron);  rs1057903 (T/C:locus-region);  rs1499821 (A/G:intron);  rs2292620 (T/C:intron);  rs1996220 (C/T:intron);  rs3081330 (-/TAT:intron);  rs885445 (C/T:intron);  rs731207 (C/G:intron);  rs3138708 ((CA)/16/17/18/19/20/21/22/23/24:intron);  rs1800572 (G/A:coding-nonsyn);  rs1879442 (A/G:intron);  rs2544 (T/C:intron);  rs5393 (T/C:coding-nonsyn);  rs2129019 (G/T:intron);  
EvidenceAmplification in Prostate cancer

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Department of Urology
Universityof California, San Francisco