Human

Human Prostate Gene DataBase

Name insulin-like growth factor binding protein 3
Symbol IGFBP3
Aliases
Gene Product
  • insulin-like growth factor binding protein 3
Category
  • Mutation in Prostate cancer
UniGeneHs.77326
OMIM146732
Locus3486
SummaryMember of the insulin-like growth factor binding family of proteins; may bind to and modulate insulin-like growth factor activity
Gene Ontology
Expression
EST (929 ESTs, 194 libraries)
Tissue ? Frequency ? Count ?
adipose (2/10)0.098 2/2445
bone (2/13)0.022 16/26211
bone marrow (1/263)0.067 1/38555
brain (13/204)0.002 25/362011
cervix (1/7)0.025 1/28115
colon (10/853)0.011 18/165626
connective tissue (1/1)0.015 1/1301
ear (1/2)0.008 5/12660
embryo (2/19)0.001 2/37976
esophagus (1/6)0.014 2/3022
eye (6/33)0.018 10/93836
foreskin (1/4)0.014 14/20040
germ cell (2/7)0.003 2/57383
head and neck (9/990)1.000 10/79796
heart (2/22)0.003 18/55494
intestine (1/4)0.002 1/11528
kidney (10/86)0.014 170/132968
liver (4/38)0.005 18/46472
lung (15/312)0.006 47/245386
nervous (4/475)0.036 5/43438
oral cavity (1/18)0.117 7/44567
ovary (3/144)0.053 46/81880
pancreas (6/33)0.054 72/117255
parathyroid (1/4)0.001 1/19377
placenta (15/342)0.035 161/157762
prostate (7/291)0.003 8/109871
skin (3/31)0.003 6/100815
spleen (2/7)0.017 7/9511
stomach (9/312)0.021 81/129930
t cells (1/2)0.012 2/4729
testis (2/171)0.001 2/117531
uncharacterized tissue (46/1773)0.035 124/713325
uterus (10/212)0.020 44/155110
SAGE (7075204 tags, 132 libraries)
Tissue ? Frequency ? Count ?
blood (1/1)0.778 2/97046
brain (11/19)0.547 31/1575438
cerebellum (1/1)0.675 3/153840
colon (8/8)0.645 27/853386
eye (3/6)0.735 9/583333
heart (1/1)0.242 3/253071
kidney (2/2)0.485 3/115792
liver (1/1)0.706 5/133722
lung (1/1)0.071 1/89143
mammary gland (8/19)0.794 25/1055298
muscle (2/2)0.613 7/107728
ovary (6/10)0.494 11/366439
pancreas (3/8)0.193 3/121165
prostate (6/13)0.938 18/516821
skin (3/7)1.000 3/37639
stomach (3/3)0.353 4/232200
uncharacterized tissue (10/22)0.458 23/730564
vascular (1/3)0.538 3/52579
SNPrs2515696 (G/C:exception);  rs2132570 (A/G:locus-region);  rs9911 (G/A:mrna-utr);  rs2645036 (C/G:exception);  rs2453839 (G/T:mrna-utr);  rs2471549 (C/G:exception);  rs2854744 (G/A:exception);  rs6670 (A/T:mrna-utr);  rs2453837 (C/T:exception);  rs3110696 (A/G:exception);  rs1050566 (C/T:mrna-utr);  
EvidenceMutation in Prostate cancer

© 2002, PGDB, All Rights Reserved.
Department of Urology
Universityof California, San Francisco