| Name | insulin-like growth factor binding protein 3 |
| Symbol | IGFBP3 |
| Aliases | |
| Gene Product | - insulin-like growth factor binding protein 3
|
| Category | - Mutation in Prostate cancer
|
| UniGene | Hs.77326 |
| OMIM | 146732 |
| Locus | 3486 |
| Summary | Member of the insulin-like growth factor binding family of proteins; may bind to and modulate insulin-like growth factor activity |
| Gene Ontology | |
| Expression | | EST (929 ESTs, 194 libraries) |
| Tissue ? |
Frequency ? |
Count ? |
| adipose (2/10) |  | 2/2445 |
| bone (2/13) | | 16/26211 |
| bone marrow (1/263) | | 1/38555 |
| brain (13/204) | | 25/362011 |
| cervix (1/7) | | 1/28115 |
| colon (10/853) | | 18/165626 |
| connective tissue (1/1) | | 1/1301 |
| ear (1/2) | | 5/12660 |
| embryo (2/19) | | 2/37976 |
| esophagus (1/6) | | 2/3022 |
| eye (6/33) | | 10/93836 |
| foreskin (1/4) | | 14/20040 |
| germ cell (2/7) | | 2/57383 |
| head and neck (9/990) | | 10/79796 |
| heart (2/22) | | 18/55494 |
| intestine (1/4) | | 1/11528 |
| kidney (10/86) | | 170/132968 |
| liver (4/38) | | 18/46472 |
| lung (15/312) | | 47/245386 |
| nervous (4/475) | | 5/43438 |
| oral cavity (1/18) | | 7/44567 |
| ovary (3/144) | | 46/81880 |
| pancreas (6/33) | | 72/117255 |
| parathyroid (1/4) | | 1/19377 |
| placenta (15/342) | | 161/157762 |
| prostate (7/291) |  | 8/109871 |
| skin (3/31) | | 6/100815 |
| spleen (2/7) | | 7/9511 |
| stomach (9/312) | | 81/129930 |
| t cells (1/2) | | 2/4729 |
| testis (2/171) | | 2/117531 |
| uncharacterized tissue (46/1773) | | 124/713325 |
| uterus (10/212) | | 44/155110 |
|
| SAGE (7075204 tags, 132 libraries) |
| Tissue ? |
Frequency ? |
Count ? |
| blood (1/1) | | 2/97046 |
| brain (11/19) | | 31/1575438 |
| cerebellum (1/1) | | 3/153840 |
| colon (8/8) | | 27/853386 |
| eye (3/6) | | 9/583333 |
| heart (1/1) | | 3/253071 |
| kidney (2/2) | | 3/115792 |
| liver (1/1) | | 5/133722 |
| lung (1/1) | | 1/89143 |
| mammary gland (8/19) | | 25/1055298 |
| muscle (2/2) | | 7/107728 |
| ovary (6/10) | | 11/366439 |
| pancreas (3/8) | | 3/121165 |
| prostate (6/13) | | 18/516821 |
| skin (3/7) | | 3/37639 |
| stomach (3/3) | | 4/232200 |
| uncharacterized tissue (10/22) | | 23/730564 |
| vascular (1/3) | | 3/52579 |
|
|
| SNP | rs2515696 (G/C:exception); rs2132570 (A/G:locus-region); rs9911 (G/A:mrna-utr); rs2645036 (C/G:exception); rs2453839 (G/T:mrna-utr); rs2471549 (C/G:exception); rs2854744 (G/A:exception); rs6670 (A/T:mrna-utr); rs2453837 (C/T:exception); rs3110696 (A/G:exception); rs1050566 (C/T:mrna-utr); |
| Evidence | Mutation in Prostate cancer
|
