| Name | ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) |
| Symbol | RNASEL |
| Aliases | HPC1; RNS4; PRCA1; ribonuclease 4 |
| Gene Product | - ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
|
| Category | - Mutation in Prostate cancer
|
| UniGene | Hs.56156 |
| OMIM | 180435 |
| Locus | 6041 |
| Expression | | EST (43 ESTs, 35 libraries) |
| Tissue ? |
Frequency ? |
Count ? |
| bone (1/13) |  | 1/26211 |
| cartilage (1/5) | | 1/11018 |
| cervix (1/7) | | 1/28115 |
| eye (1/33) | | 1/93836 |
| germ cell (1/7) | | 1/57383 |
| head and neck (1/990) | | 1/79796 |
| heart (1/22) | | 2/55494 |
| kidney (1/86) | | 1/132968 |
| liver (1/38) | | 1/46472 |
| lung (6/312) | | 6/245386 |
| oral cavity (1/18) | | 4/44567 |
| pancreas (1/33) | | 1/117255 |
| parathyroid (1/4) | | 2/19377 |
| prostate (1/291) |  | 1/109871 |
| skin (2/31) | | 2/100815 |
| testis (1/171) | | 1/117531 |
| uncharacterized tissue (10/1773) | | 13/713325 |
| uterus (3/212) | | 3/155110 |
|
| SAGE (3151605 tags, 54 libraries) |
| Tissue ? |
Frequency ? |
Count ? |
| blood (1/1) | | 3/48523 |
| brain (15/19) | | 21/1167891 |
| colon (4/8) | | 4/220511 |
| eye (2/6) | | 3/310030 |
| liver (1/1) | | 3/200583 |
| lung (1/1) | | 3/178286 |
| mammary gland (5/19) | | 12/217413 |
| ovary (3/10) | | 3/71359 |
| prostate (3/13) | | 4/152267 |
| stomach (1/3) | | 1/66032 |
| uncharacterized tissue (8/22) | | 8/442542 |
| vascular (1/3) | | 2/76168 |
|
|
| SNP | rs1144567 (C/A:intron); rs501286 (T/C:intron); rs2274509 (A/G:locus-region); rs627928 (T/G:coding-nonsyn); rs579006 (C/T:intron); rs516134 (G/A:intron); rs618685 (G/A:locus-region); rs589974 (A/G:locus-region); rs620070 (A/G:locus-region); rs533259 (T/C:intron); rs611280 (T/A:intron); rs486907 (G/A:coding-nonsyn); rs557934 (G/T:intron); rs672527 (T/C:intron); rs682585 (G/A:locus-region); rs672018 (G/A:intron); |
| Evidence | Mutation in Prostate cancer
|
