PCAP - predisposing for prostate cancer

Human Prostate Gene DataBase

Name	predisposing for prostate cancer
Symbol	PCAP
Aliases	HPC2; PRCA2; prostate cancer susceptibility 2
Category	Gross deletion in Prostate cancer Mutation in Prostate cancer
OMIM	602759
Locus	7834
Evidence	Gross deletion in Prostate cancer Loss of heterozygosity of the putative prostate cancer susceptibility geneHPC2/ELAC2 is uncommon in sporadic and familial prostate cancer. Cancer Res 2001 Dec 15;61(24):8651-3. Mutation in Prostate cancer ELAC2/HPC2 involvement in hereditary and sporadic prostate cancer. Cancer Res 2001 Aug 15;61(16):6038-41. Evaluation of linkage and association of HPC2/ELAC2 in patients withfamilial or sporadic prostate cancer. Am J Hum Genet 2001 Apr;68(4):901-11.