| Name | eukaryotic translation initiation factor 3, subunit 3 (gamma, 40kD) |
| Symbol | EIF3S3 |
| Aliases | EIF3-P40; EIF3-GAMMA |
| Gene Product | - eukaryotic translation initiation factor 3, subunit 3 (gamma, 40kD)
|
| Category | - Amplification in Prostate cancer
|
| UniGene | Hs.58189 |
| OMIM | 603912 |
| Locus | 8667 |
| Summary | Translation initiation factor 3, subunit 3 (gamma, 40kD); subunit of the complex that stabilizes initiator Met-tRNA binding to 40S subunits |
| Gene Ontology | |
| Expression | | EST (883 ESTs, 259 libraries) |
| Tissue ? |
Frequency ? |
Count ? |
| adrenal gland (3/15) |  | 4/17521 |
| b cells (1/1) |  | 33/16734 |
| blood (3/27) |  | 12/40686 |
| bone (4/13) |  | 7/26211 |
| bone marrow (5/263) |  | 6/38555 |
| brain (19/204) |  | 51/362011 |
| cartilage (2/5) |  | 4/11018 |
| cervix (2/7) |  | 11/28115 |
| colon (25/853) |  | 115/165626 |
| embryo (4/19) |  | 10/37976 |
| eye (6/33) |  | 39/93836 |
| gall (1/3) |  | 1/2502 |
| germ cell (1/7) |  | 1/57383 |
| head and neck (6/990) |  | 8/79796 |
| heart (3/22) |  | 22/55494 |
| intestine (1/4) |  | 3/11528 |
| kidney (9/86) |  | 25/132968 |
| liver (2/38) |  | 4/46472 |
| lung (16/312) |  | 59/245386 |
| muscle (6/21) |  | 16/71297 |
| nervous (6/475) |  | 8/43438 |
| oral cavity (3/18) |  | 4/44567 |
| ovary (12/144) |  | 30/81880 |
| pancreas (7/33) |  | 25/117255 |
| parathyroid (1/4) |  | 5/19377 |
| placenta (6/342) |  | 44/157762 |
| prostate (10/291) |  | 16/109871 |
| skin (10/31) |  | 55/100815 |
| spleen (3/7) |  | 8/9511 |
| stomach (11/312) |  | 23/129930 |
| testis (8/171) |  | 38/117531 |
| thyroid (1/24) |  | 1/6853 |
| umbilical cord (1/3) |  | 2/6185 |
| uncharacterized tissue (48/1773) |  | 129/713325 |
| uterus (12/212) |  | 62/155110 |
|
| SAGE (24495848 tags, 466 libraries) |
| Tissue ? |
Frequency ? |
Count ? |
| blood (1/1) |  | 8/145569 |
| brain (19/19) |  | 205/5187885 |
| cerebellum (1/1) |  | 6/153840 |
| colon (8/8) |  | 141/2133171 |
| eye (6/6) |  | 66/2393061 |
| foreskin (2/2) |  | 5/19256 |
| heart (1/1) |  | 19/421785 |
| kidney (2/2) |  | 13/157649 |
| liver (1/1) |  | 5/200583 |
| lung (1/1) |  | 26/624001 |
| mammary gland (19/19) |  | 215/2876725 |
| muscle (2/2) |  | 14/323162 |
| ovary (9/10) |  | 86/793375 |
| pancreas (8/8) |  | 68/823341 |
| prostate (13/13) |  | 210/2109959 |
| skin (7/7) |  | 23/216152 |
| stomach (3/3) |  | 44/1105995 |
| uncharacterized tissue (21/22) |  | 192/3869246 |
| vascular (3/3) |  | 50/941093 |
|
|
| SNP | rs1529945 (C/T:intron);  rs2366 (T/G:intron);  rs10054 (G/C:mrna-utr);  rs1436767 (A/G:intron);  rs2278491 (T/C:locus-region);  rs1317271 (A/T:intron);  rs1347626 (C/T:locus-region);  rs1804926 (A/C:coding-nonsyn);  rs1343663 (C/T:intron);  rs1865889 (A/G:intron);   |
| Evidence | Amplification in Prostate cancer
|