| Name | acid phosphatase, prostate |
| Symbol | ACPP |
| Aliases | PAP |
| Gene Product | - prostatic acid phosphatase precursor
|
| Category | |
| UniGene | Hs.1852 |
| OMIM | 171790 |
| Locus | 55 |
| Summary | Prostatic acid phosphatase precursor catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. ACPP is synthesized under androgen regulation and secreted by the epithelial cells of the prostrate gland. Sequence comparison has indicated the presence of several polymorphisms. ACPP undergoes alternative splicing in the 3' UTR. |
| Gene Ontology | |
| Expression | | EST (483 ESTs, 56 libraries) |
| Tissue ? |
Frequency ? |
Count ? |
| brain (1/204) |  | 2/362011 |
| colon (3/853) | | 5/165626 |
| germ cell (1/7) | | 2/57383 |
| head and neck (1/990) | | 3/79796 |
| heart (1/22) | | 3/55494 |
| liver (1/38) | | 5/46472 |
| lung (2/312) | | 2/245386 |
| muscle (2/21) | | 8/71297 |
| pancreas (1/33) | | 2/117255 |
| placenta (1/342) | | 1/157762 |
| prostate (36/291) |  | 351/109871 |
| stomach (2/312) | | 8/129930 |
| uncharacterized tissue (4/1773) | | 91/713325 |
|
| SAGE (24209662 tags, 489 libraries) |
| Tissue ? |
Frequency ? |
Count ? |
| blood (1/1) | | 3/97046 |
| brain (19/19) | | 287/5283409 |
| cerebellum (1/1) | | 26/153840 |
| colon (8/8) | | 191/1603458 |
| eye (6/6) | | 77/2126577 |
| foreskin (2/2) | | 10/38774 |
| heart (1/1) | | 4/337428 |
| kidney (2/2) | | 18/315298 |
| liver (1/1) | | 6/334305 |
| lung (1/1) | | 1/89143 |
| mammary gland (18/19) | | 146/2547986 |
| muscle (2/2) | | 8/161581 |
| ovary (9/10) | | 73/1041931 |
| pancreas (8/8) | | 140/1110849 |
| prostate (13/13) | | 355/3552652 |
| skin (6/7) | | 15/149746 |
| stomach (3/3) | | 19/596464 |
| uncharacterized tissue (20/22) | | 261/3875017 |
| vascular (3/3) | | 33/794158 |
|
|
| SNP | rs14192 (C/T:intron); rs218699 (G/A:locus-region); rs1804122 (A/G:intron); rs2285060 (T/A:intron); rs12817 (G/T:intron); rs2198765 (C/T:mrna-utr); rs849146 (A/G:intron); rs13131 (A/G:intron); rs2310165 (A/T:intron); rs2239698 (C/A:intron); rs972773 (A/G:intron); rs10115 (A/G:intron); rs860264 (G/A:intron); rs2071505 (A/G:intron); rs2793144 (T/C:intron); rs2290540 (C/T:intron); rs2310229 (G/T:intron); rs15096 (A/G:intron); rs1042301 (C/T:intron); rs2605406 (G/A:locus-region); rs974844 (T/G:intron); rs1505824 (T/C:intron); rs2857044 (A/T:intron); rs1062686 (G/A:intron); rs309987 (G/A:intron); |
| Evidence | Other in Normal prostate
|
