| Name | neurotrophic tyrosine kinase, receptor, type 1 |
| Symbol | NTRK1 |
| Aliases | MTC; TRK; TRKA; Oncogene TRK |
| Gene Product | - neurotrophic tyrosine kinase, receptor, type 1
|
| Category | - Mutation in Prostate cancer
|
| UniGene | Hs.85844 |
| OMIM | 191315 |
| Locus | 4914 |
| Summary | Nerve growth factor receptor, type 1; member of the type I tyrosine kinase receptor family |
| Gene Ontology | |
| Expression | | EST (1402 ESTs, 362 libraries) |
| Tissue ? |
Frequency ? |
Count ? |
| adrenal gland (2/15) |  | 5/17521 |
| b cells (1/1) | | 29/16734 |
| blood (7/27) | | 22/40686 |
| bone (4/13) | | 20/26211 |
| bone marrow (13/263) | | 22/38555 |
| brain (29/204) | | 113/362011 |
| cartilage (1/5) | | 3/11018 |
| cervix (3/7) | | 23/28115 |
| colon (26/853) | | 60/165626 |
| ear (1/2) | | 3/12660 |
| embryo (3/19) | | 7/37976 |
| esophagus (1/6) | | 2/3022 |
| eye (6/33) | | 39/93836 |
| foreskin (1/4) | | 11/20040 |
| gall (2/3) | | 2/2502 |
| germ cell (4/7) | | 15/57383 |
| head and neck (12/990) | | 14/79796 |
| heart (3/22) | | 20/55494 |
| intestine (1/4) | | 10/11528 |
| kidney (9/86) | | 59/132968 |
| liver (5/38) | | 10/46472 |
| lung (24/312) | | 96/245386 |
| muscle (6/21) | | 22/71297 |
| nervous (7/475) | | 12/43438 |
| oral cavity (3/18) | | 8/44567 |
| ovary (10/144) | | 41/81880 |
| pancreas (8/33) | | 48/117255 |
| parathyroid (1/4) | | 2/19377 |
| placenta (11/342) | | 63/157762 |
| prostate (16/291) |  | 92/109871 |
| skin (8/31) | | 76/100815 |
| spleen (1/7) | | 2/9511 |
| stomach (18/312) | | 52/129930 |
| t cells (1/2) | | 3/4729 |
| testis (9/171) | | 54/117531 |
| thymus (1/17) | | 2/5021 |
| thyroid (2/24) | | 2/6853 |
| umbilical cord (1/3) | | 2/6185 |
| uncharacterized tissue (78/1773) | | 238/713325 |
| uterus (18/212) | | 87/155110 |
|
| SAGE (50142956 tags, 981 libraries) |
| Tissue ? |
Frequency ? |
Count ? |
| blood (1/1) | | 30/582276 |
| brain (19/19) | | 752/10798973 |
| cerebellum (1/1) | | 21/461520 |
| colon (8/8) | | 286/4131113 |
| eye (6/6) | | 222/4110884 |
| foreskin (2/2) | | 12/48271 |
| heart (1/1) | | 44/1096641 |
| kidney (2/2) | | 35/591480 |
| liver (1/1) | | 21/334305 |
| lung (1/1) | | 39/980573 |
| mammary gland (19/19) | | 468/5489407 |
| muscle (2/2) | | 274/1184964 |
| ovary (10/10) | | 239/2125447 |
| pancreas (8/8) | | 184/1897919 |
| prostate (13/13) | | 342/4724185 |
| skin (7/7) | | 64/322857 |
| stomach (3/3) | | 111/1527489 |
| uncharacterized tissue (21/22) | | 559/7848978 |
| vascular (3/3) | | 130/1885674 |
|
|
| SNP | rs2644613 (C/A:intron); rs2274496 (T/G:intron); rs1007210 (A/G:coding-nonsyn); rs2768754 (T/G:intron); rs2644603 (C/T:intron); rs1800872 (T/C:intron); rs876359 (A/G:locus-region); rs1410082 (A/G:intron); rs6333 (C/T:coding-nonsyn); |
| Evidence | Mutation in Prostate cancer
|
