| Name | plasminogen activator, urokinase |
| Symbol | PLAU |
| Aliases | URK |
| Gene Product | - plasminogen activator, urokinase
|
| Category | - Amplification in Prostate cancer
|
| UniGene | Hs.77274 |
| OMIM | 191840 |
| Locus | 5328 |
| Summary | Urokinase plasminogen activator; serine protease that cleaves plasminogen to form plasmin |
| Gene Ontology | |
| Expression | | EST (279 ESTs, 124 libraries) |
| Tissue ? |
Frequency ? |
Count ? |
| bone (2/13) |  | 5/26211 |
| brain (3/204) | | 4/362011 |
| cervix (1/7) | | 2/28115 |
| colon (11/853) | | 22/165626 |
| esophagus (1/6) | | 1/3022 |
| eye (1/33) | | 4/93836 |
| gall (1/3) | | 1/2502 |
| germ cell (2/7) | | 2/57383 |
| head and neck (18/990) | | 25/79796 |
| heart (1/22) | | 2/55494 |
| kidney (5/86) | | 9/132968 |
| liver (1/38) | | 10/46472 |
| lung (16/312) | | 41/245386 |
| muscle (1/21) | | 2/71297 |
| ovary (3/144) | | 7/81880 |
| pancreas (5/33) | | 39/117255 |
| parathyroid (1/4) | | 1/19377 |
| placenta (4/342) | | 12/157762 |
| prostate (2/291) |  | 5/109871 |
| skin (3/31) | | 3/100815 |
| stomach (8/312) | | 20/129930 |
| testis (3/171) | | 4/117531 |
| uncharacterized tissue (24/1773) | | 42/713325 |
| uterus (6/212) | | 15/155110 |
|
| SAGE (9642029 tags, 201 libraries) |
| Tissue ? |
Frequency ? |
Count ? |
| blood (1/1) | | 5/242615 |
| brain (17/19) | | 71/2291282 |
| cerebellum (1/1) | | 7/153840 |
| colon (6/8) | | 38/798276 |
| eye (3/6) | | 6/272894 |
| foreskin (1/2) | | 1/9497 |
| heart (1/1) | | 1/84357 |
| kidney (2/2) | | 4/157649 |
| lung (1/1) | | 2/178286 |
| mammary gland (12/19) | | 28/933186 |
| muscle (2/2) | | 3/161581 |
| ovary (8/10) | | 115/779731 |
| pancreas (8/8) | | 71/817258 |
| prostate (9/13) | | 82/743176 |
| skin (4/7) | | 13/80975 |
| stomach (2/3) | | 6/136465 |
| uncharacterized tissue (16/22) | | 48/1485463 |
| vascular (3/3) | | 13/315498 |
|
|
| SNP | rs2227579 (C/T:locus-region); rs2227551 (G/-:locus-region); rs1804874 (G/T:locus-region); rs1916340 (A/C:locus-region); rs1050046 (C/G:locus-region); rs4065 (C/T:locus-region); rs2459449 (T/C:locus-region); |
| Evidence | Amplification in Prostate cancer
|
