Human

Human Prostate Gene DataBase

Name tumor necrosis factor receptor superfamily, member 6
Symbol TNFRSF6
Aliases FAS; APT1; CD95; APO-1; apoptosis (APO-1) antigen 1
Gene Product
  • apoptosis (APO-1) antigen 1
Category
  • Gross deletion in Prostate cancer
UniGeneHs.82359
OMIM134637
Locus355
SummaryTumor necrosis factor receptor superfamily, member 16; activates cell death upon ligand binding
Gene Ontology
Expression
EST (100 ESTs, 54 libraries)
Tissue ? Frequency ? Count ?
adrenal gland (1/15)0.010 1/17521
blood (1/27)0.025 1/40686
bone marrow (1/263)0.288 1/38555
brain (2/204)0.003 5/362011
cervix (1/7)0.001 1/28115
colon (1/853)0.002 1/165626
embryo (1/19)0.001 1/37976
eye (2/33)0.083 19/93836
foreskin (1/4)0.001 1/20040
germ cell (1/7)0.001 1/57383
kidney (2/86)0.004 3/132968
liver (2/38)0.002 2/46472
lung (6/312)0.004 10/245386
muscle (1/21)0.004 2/71297
oral cavity (1/18)0.002 4/44567
ovary (2/144)0.010 4/81880
pancreas (1/33)0.002 1/117255
placenta (2/342)0.002 4/157762
prostate (1/291)1.000 1/109871
skin (1/31)0.073 1/100815
stomach (2/312)0.008 3/129930
testis (2/171)0.001 2/117531
uncharacterized tissue (15/1773)0.065 22/713325
uterus (4/212)0.001 9/155110
SAGE (10510787 tags, 201 libraries)
Tissue ? Frequency ? Count ?
blood (1/1)0.509 4/97046
brain (18/19)0.281 63/2312542
cerebellum (1/1)0.160 2/102560
colon (8/8)0.291 29/914792
eye (4/6)0.322 13/588235
foreskin (1/2)0.422 1/9759
heart (1/1)0.256 5/337428
kidney (1/2)0.257 2/32078
liver (1/1)0.185 3/133722
lung (1/1)0.185 3/267429
mammary gland (16/19)0.536 54/1156361
muscle (1/2)0.076 1/53875
ovary (8/10)0.448 19/401199
pancreas (4/8)0.363 13/289308
prostate (9/13)0.285 33/1140303
skin (4/7)1.000 9/83911
stomach (2/3)0.498 10/274002
uncharacterized tissue (15/22)0.597 57/1966324
vascular (3/3)0.193 6/349913
SNPrs2234978 (C/T:exception);  rs1977389 (A/C:exception);  rs1571011 (A/G:exception);  rs2147418 (G/A:exception);  rs1571019 (A/G:exception);  rs1468063 (A/G:mrna-utr);  rs982764 (A/G:exception);  rs3074154 (TTTTT/-:exception);  rs2862833 (C/T:locus-region);  rs2031610 (A/G:exception);  rs2182408 (A/G:exception);  rs2148286 (G/A:exception);  rs1159120 (C/T:exception);  rs2296600 (T/C:exception);  rs1051070 (A/T:mrna-utr);  rs1926190 (A/G:exception);  
EvidenceGross deletion in Prostate cancer

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Department of Urology
Universityof California, San Francisco