| Name | estrogen receptor 1 |
| Symbol | ESR1 |
| Aliases | ESR; Era; NR3A1; estrogen receptor 1 (alpha) |
| Gene Product | |
| Category | - Methylation in Benign prostate hyperplasia
- Methylation in Prostate cancer
|
| UniGene | Hs.1657 |
| OMIM | 133430 |
| Locus | 2099 |
| Summary | Estrogen receptor; nuclear receptor transcription factor activated by ligand-binding, involved in hormone-mediated inhibition of gene expression |
| Gene Ontology | |
| Expression | | EST (77 ESTs, 33 libraries) |
| Tissue ? |
Frequency ? |
Count ? |
| adrenal gland (1/15) |  | 1/17521 |
| embryo (1/19) | | 1/37976 |
| heart (3/22) | | 3/55494 |
| kidney (1/86) | | 2/132968 |
| lung (2/312) | | 3/245386 |
| muscle (1/21) | | 2/71297 |
| oral cavity (1/18) | | 1/44567 |
| ovary (4/144) | | 10/81880 |
| pancreas (2/33) | | 2/117255 |
| prostate (1/291) |  | 6/109871 |
| testis (2/171) | | 3/117531 |
| uncharacterized tissue (6/1773) | | 6/713325 |
| uterus (8/212) | | 37/155110 |
|
| SAGE (4033982 tags, 76 libraries) |
| Tissue ? |
Frequency ? |
Count ? |
| brain (12/19) | | 17/928128 |
| cerebellum (1/1) | | 1/51280 |
| colon (4/8) | | 9/336256 |
| eye (3/6) | | 8/474070 |
| heart (1/1) | | 1/84357 |
| kidney (1/2) | | 1/41857 |
| mammary gland (10/19) | | 26/816774 |
| ovary (4/10) | | 9/115475 |
| pancreas (1/8) | | 1/32226 |
| prostate (6/13) | | 7/352501 |
| skin (3/7) | | 6/65617 |
| stomach (1/3) | | 1/25302 |
| uncharacterized tissue (8/22) | | 18/657560 |
| vascular (1/3) | | 1/52579 |
|
|
| SNP | rs867239 (A/G:locus-region); rs722207 (T/G:intron); rs1569788 (C/T:intron); rs2982894 (C/A:mrna-utr); rs2228480 (A/G:coding-nonsyn); rs2347923 (A/C:intron); rs3071036 (-/TGTGTGTG:intron); rs2982683 (A/G:intron); rs985694 (C/T:intron); rs532010 (T/C:intron); rs2011885 (A/G:intron); rs3068837 (CGT/-:intron); rs2071454 (T/G:locus-region); rs1514347 (A/G:intron); rs872921 (G/T:mrna-utr); rs2459107 (A/G:intron); rs746432 (C/G:coding-nonsyn); rs988328 (A/G:intron); rs926777 (A/G:intron); rs2813542 (G/A:locus-region); rs1801132 (C/G:coding-nonsyn); rs1967507 (C/T:intron); rs2504073 (A/G:intron); rs750686 (A/G:intron); rs3138774 ((TA)/23/24/25/26/27/28/29/30/31/32/33/34/35/36/37/38/39:locus-region); rs2179922 (T/C:intron); rs2860321 (C/T:intron); rs2474148 (G/T:intron); rs1983664 (G/T:intron); rs2747644 (C/T:mrna-utr); rs722029 (C/G:mrna-utr); rs1884049 (A/C:intron); rs576330 (C/T:intron); rs2223921 (A/C:intron); rs1033181 (A/G:intron); rs1913474 (C/T:intron); rs3003917 (G/A:intron); rs974276 (C/T:intron); rs2144025 (T/C:intron); rs932477 (G/T:intron); rs985191 (A/C:intron); rs726281 (A/G:intron); rs2207396 (G/A:intron); rs728523 (A/G:intron); rs1884151 (A/G:intron); rs1062577 (T/A:mrna-utr); rs2273206 (A/G:intron); rs2207230 (T/C:intron); rs3020351 (G/A:intron); rs2992993 (T/A:intron); rs2348078 (G/C:intron); rs2347867 (A/C:intron); rs749491 (C/T:intron); rs2175898 (G/A:intron); rs1355930 (A/G:intron); rs2077647 (A/G:coding-nonsyn); rs3020314 (T/C:intron); |
| Evidence | Methylation in Benign prostate hyperplasia
Methylation in Prostate cancer
|
