Human

Human Prostate Gene DataBase

Name SRY (sex determining region Y)-box 2
Symbol SOX2
Aliases
Category
  • Amplification in Prostate cancer
UniGeneHs.816
OMIM184429
Locus6657
SummaryVery strongly similar to murine Sox2; may be a transcription factor that complexes with murine Pou5f1
Gene Ontology
Expression
EST (170 ESTs, 54 libraries)
Tissue ? Frequency ? Count ?
brain (12/204)0.007 63/362011
ear (1/2)0.006 2/12660
embryo (2/19)0.003 4/37976
esophagus (1/6)0.014 1/3022
eye (3/33)0.007 3/93836
germ cell (2/7)0.010 10/57383
head and neck (2/990)1.000 2/79796
heart (1/22)0.001 1/55494
intestine (1/4)0.004 1/11528
kidney (1/86)0.072 1/132968
lung (9/312)0.034 39/245386
muscle (1/21)0.024 14/71297
nervous (1/475)0.304 1/43438
pancreas (1/33)0.032 4/117255
prostate (2/291)0.028 2/109871
stomach (1/312)0.011 3/129930
testis (1/171)0.001 1/117531
thymus (1/17)0.013 1/5021
uncharacterized tissue (11/1773)0.009 17/713325
SAGE (1105903 tags, 21 libraries)
Tissue ? Frequency ? Count ?
blood (1/1)0.380 1/48523
brain (5/19)0.379 6/284043
cerebellum (1/1)0.360 1/51280
colon (3/8)0.190 3/167164
eye (1/6)0.180 1/102359
mammary gland (2/19)0.149 2/124267
ovary (1/10)0.190 1/48552
pancreas (2/8)0.380 2/73712
prostate (1/13)0.418 1/44159
skin (2/7)1.000 2/28426
stomach (1/3)0.279 1/66032
uncharacterized tissue (1/22)0.137 1/67386
EvidenceAmplification in Prostate cancer

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Department of Urology
Universityof California, San Francisco