Human

Human Prostate Gene DataBase
Name vitamin D (1,25- dihydroxyvitamin D3) receptor
Symbol VDR
Aliases NR1I1
Gene Product
  • vitamin D (1,25- dihydroxyvitamin D3) receptor
Category
  • Linkage in Prostate cancer
  • Polymorphism in Benign prostate hyperplasia
  • Polymorphism in Prostate cancer
UniGeneHs.2062
OMIM601769
Locus7421
SummaryVitamin D receptor (1,25- dihydroxyvitamin D-3 receptor); zinc-finger DNA-binding transcription factor
Gene Ontology
Expression
EST (192 ESTs, 76 libraries)
Tissue ? Frequency ? Count ?
blood (2/27)0.018 2/40686
bone marrow (1/263)0.614 1/38555
brain (3/204)0.063 8/362011
cartilage (1/5)0.065 1/11018
cervix (2/7)0.069 3/28115
colon (6/853)0.113 15/165626
embryo (1/19)0.017 2/37976
germ cell (2/7)0.006 3/57383
head and neck (3/990)0.388 3/79796
heart (1/22)0.041 7/55494
kidney (3/86)0.017 6/132968
lung (4/312)0.047 12/245386
oral cavity (1/18)0.029 6/44567
ovary (4/144)0.158 15/81880
pancreas (3/33)0.031 6/117255
parathyroid (1/4)0.399 38/19377
placenta (2/342)1.000 5/157762
prostate (3/291)0.036 8/109871
skin (3/31)0.009 5/100815
stomach (7/312)0.076 9/129930
testis (1/171)0.010 2/117531
uncharacterized tissue (18/1773)0.052 28/713325
uterus (3/212)0.015 6/155110
SAGE (14476064 tags, 288 libraries)
Tissue ? Frequency ? Count ?
blood (1/1)0.310 7/97046
brain (19/19)0.454 198/2877558
cerebellum (1/1)0.869 19/102560
colon (8/8)0.869 141/1660661
eye (6/6)1.000 103/1306786
foreskin (2/2)0.580 5/19256
heart (1/1)0.092 3/168714
kidney (2/2)0.495 13/157649
liver (1/1)0.117 3/133722
lung (1/1)0.150 6/89143
mammary gland (18/19)0.513 148/1777357
muscle (2/2)0.145 7/107728
ovary (9/10)0.465 53/620827
pancreas (8/8)0.552 65/679096
prostate (13/13)0.371 73/1578379
skin (5/7)0.474 11/89770
stomach (3/3)0.134 8/368665
uncharacterized tissue (21/22)0.631 192/2138898
vascular (3/3)0.388 28/502249
SNPrs2408876 (T/A:mrna-utr);  rs2283342 (C/T:intron);  rs1808207 (C/T:intron);  rs739837 (G/T:mrna-utr);  rs731236 (C/T:coding-nonsyn);  rs1540339 (A/G:intron);  rs2248098 (T/C:intron);  rs2189478 (C/A:intron);  rs1042935 (C/T:mrna-utr);  rs2525043 (T/C:intron);  rs987849 (C/T:intron);  rs2239179 (C/T:intron);  rs2107301 (C/T:intron);  rs2229829 (C/A:coding-nonsyn);  rs2254210 (A/G:mrna-utr);  rs2544043 (C/G:mrna-utr);  rs9729 (A/C:mrna-utr);  rs2853562 (C/T:locus-region);  rs1989969 (C/T:locus-region);  rs757343 (A/G:intron);  rs2238135 (C/T:intron);  rs1544410 (A/G:intron);  rs12088 (G/C:mrna-utr);  rs2853560 (C/T:intron);  rs886441 (C/T:intron);  
EvidenceLinkage in Prostate cancer Polymorphism in Benign prostate hyperplasia Polymorphism in Prostate cancer
© 2002, PGDB, All Rights Reserved.
Department of Urology
Universityof California, San Francisco