Human

Human Kidney Gene DataBase
Name glutathione S-transferase pi
Symbol GSTP1
Aliases PI; DFN7; GST3; FAEES3; deafness, X-linked 7; fatty acid ethyl ester synthase III
Gene Product
  • glutathione transferase
Category
UniGene Hs.411509 
Reference Sequence
mRNA: NM_000852 Protein: NP_000843
OMIM and SNP
OMIM: 134660 SNP: NCBI SNP
Locus
LocusLink: 2950Chromosome: 11Cytoband: 11q13 UCSC Genome Map Eesembl Genome Map
SummaryGlutathione S-transferases (GSTs) are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical, immunologic, and structural properties, the soluble GSTs are categorized into 4 main classes: alpha, mu, pi, and theta. The glutathione S-transferase pi gene (GSTP1) is a polymorphic gene encoding active, functionally different GSTP1 variant proteins that are thought to function in xenobiotic metabolism and play a role in susceptibility to cancer, and other diseases.
Expression
EST (1278 ESTs, 329 libraries)
Tissue Breadth ? CPM ?
adiposeBreadth of expression: 1 out of 8 libraries express this gene (12.50%)Average CPM:0.29
bloodBreadth of expression: 3 out of 32 libraries express this gene (9.38%)Average CPM:5.63
boneBreadth of expression: 7 out of 24 libraries express this gene (29.17%)Average CPM:0.40
brainBreadth of expression: 20 out of 759 libraries express this gene (2.64%)Average CPM:1.58
cartilageBreadth of expression: 9 out of 16 libraries express this gene (56.25%)Average CPM:0.20
cervixBreadth of expression: 3 out of 11 libraries express this gene (27.27%)Average CPM:0.95
colonBreadth of expression: 30 out of 930 libraries express this gene (3.23%)Average CPM:3.42
esophagusBreadth of expression: 1 out of 8 libraries express this gene (12.50%)Average CPM:0.56
eyeBreadth of expression: 10 out of 24 libraries express this gene (41.67%)Average CPM:0.54
germ cellBreadth of expression: 2 out of 6 libraries express this gene (33.33%)Average CPM:0.37
head and neckBreadth of expression: 12 out of 680 libraries express this gene (1.76%)Average CPM:2.66
heartBreadth of expression: 3 out of 26 libraries express this gene (11.54%)Average CPM:0.46
kidneyBreadth of expression: 8 out of 145 libraries express this gene (5.52%)Average CPM:0.46
liverBreadth of expression: 6 out of 65 libraries express this gene (9.23%)Average CPM:0.22
lungBreadth of expression: 25 out of 334 libraries express this gene (7.49%)Average CPM:0.64
lymph nodeBreadth of expression: 7 out of 22 libraries express this gene (31.82%)Average CPM:1.26
mammary glandBreadth of expression: 12 out of 1038 libraries express this gene (1.16%)Average CPM:0.53
muscleBreadth of expression: 3 out of 83 libraries express this gene (3.61%)Average CPM:0.10
nervousBreadth of expression: 3 out of 21 libraries express this gene (14.29%)Average CPM:0.24
oral cavityBreadth of expression: 2 out of 13 libraries express this gene (15.38%)Average CPM:1.86
ovaryBreadth of expression: 9 out of 170 libraries express this gene (5.29%)Average CPM:0.18
pancreasBreadth of expression: 6 out of 20 libraries express this gene (30.00%)Average CPM:1.59
parathyroidBreadth of expression: 1 out of 2 libraries express this gene (50.00%)Average CPM:0.11
pineal glandBreadth of expression: 1 out of 2 libraries express this gene (50.00%)Average CPM:1.43
placentaBreadth of expression: 12 out of 358 libraries express this gene (3.35%)Average CPM:0.28
prostateBreadth of expression: 12 out of 309 libraries express this gene (3.88%)Average CPM:0.05
skinBreadth of expression: 12 out of 38 libraries express this gene (31.58%)Average CPM:4.40
spleenBreadth of expression: 2 out of 15 libraries express this gene (13.33%)Average CPM:0.10
stomachBreadth of expression: 15 out of 310 libraries express this gene (4.84%)Average CPM:0.50
synoviumBreadth of expression: 1 out of 8 libraries express this gene (12.50%)Average CPM:1.21
testisBreadth of expression: 4 out of 180 libraries express this gene (2.22%)Average CPM:20.06
thymusBreadth of expression: 1 out of 23 libraries express this gene (4.35%)Average CPM:15.05
thyroidBreadth of expression: 4 out of 48 libraries express this gene (8.33%)Average CPM:2.63
uncharacterized tissueBreadth of expression: 49 out of 1739 libraries express this gene (2.82%)Average CPM:4.15
uterusBreadth of expression: 18 out of 236 libraries express this gene (7.63%)Average CPM:0.04
vascularBreadth of expression: 4 out of 18 libraries express this gene (22.22%)Average CPM:0.67
whole bodyBreadth of expression: 2 out of 12 libraries express this gene (16.67%)Average CPM:0.13
EvidenceCpG Methylation in Kidney Neoplasms

Other key publications related to this gene

© 2004, KGDB, All Rights Reserved.
Department of Urology
University of California, San Francisco