Human

Human Kidney Gene DataBase
Name complement component 3
Symbol C3
Aliases ASP; acylation-stimulating protein cleavage product
Gene Product
  • complement component 3 precursor
Category
UniGene Hs.284394 
Reference Sequence
mRNA: NM_000064 Protein: NP_000055
OMIM and SNP
OMIM: 120700 SNP: NCBI SNP
Locus
LocusLink: 718Chromosome: 19Cytoband: 19p13.3-p13.2 UCSC Genome Map Eesembl Genome Map
SummaryComplement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. People with C3 deficiency are susceptable to bacteria infection.
Expression
EST (1144 ESTs, 291 libraries)
Tissue Breadth ? CPM ?
adiposeBreadth of expression: 3 out of 8 libraries express this gene (37.50%)Average CPM:5.08
boneBreadth of expression: 4 out of 24 libraries express this gene (16.67%)Average CPM:0.28
brainBreadth of expression: 31 out of 759 libraries express this gene (4.08%)Average CPM:2.48
cartilageBreadth of expression: 3 out of 16 libraries express this gene (18.75%)Average CPM:0.99
cervixBreadth of expression: 3 out of 11 libraries express this gene (27.27%)Average CPM:0.09
colonBreadth of expression: 16 out of 930 libraries express this gene (1.72%)Average CPM:1.36
eyeBreadth of expression: 5 out of 24 libraries express this gene (20.83%)Average CPM:0.56
germ cellBreadth of expression: 3 out of 6 libraries express this gene (50.00%)Average CPM:0.73
head and neckBreadth of expression: 13 out of 680 libraries express this gene (1.91%)Average CPM:32.38
heartBreadth of expression: 1 out of 26 libraries express this gene (3.85%)Average CPM:0.21
kidneyBreadth of expression: 7 out of 145 libraries express this gene (4.83%)Average CPM:1.04
liverBreadth of expression: 19 out of 65 libraries express this gene (29.23%)Average CPM:2.00
lungBreadth of expression: 32 out of 334 libraries express this gene (9.58%)Average CPM:3.46
lymph nodeBreadth of expression: 2 out of 22 libraries express this gene (9.09%)Average CPM:2.61
mammary glandBreadth of expression: 24 out of 1038 libraries express this gene (2.31%)Average CPM:19.43
muscleBreadth of expression: 4 out of 83 libraries express this gene (4.82%)Average CPM:0.06
nervousBreadth of expression: 4 out of 21 libraries express this gene (19.05%)Average CPM:1.78
oral cavityBreadth of expression: 1 out of 13 libraries express this gene (7.69%)Average CPM:4.16
ovaryBreadth of expression: 7 out of 170 libraries express this gene (4.12%)Average CPM:1.10
pancreasBreadth of expression: 3 out of 20 libraries express this gene (15.00%)Average CPM:2.42
parathyroidBreadth of expression: 1 out of 2 libraries express this gene (50.00%)Average CPM:0.17
placentaBreadth of expression: 6 out of 358 libraries express this gene (1.68%)Average CPM:0.21
prostateBreadth of expression: 5 out of 309 libraries express this gene (1.62%)Average CPM:3.01
skinBreadth of expression: 3 out of 38 libraries express this gene (7.89%)Average CPM:0.11
spleenBreadth of expression: 2 out of 15 libraries express this gene (13.33%)Average CPM:0.82
stomachBreadth of expression: 8 out of 310 libraries express this gene (2.58%)Average CPM:8.25
testisBreadth of expression: 7 out of 180 libraries express this gene (3.89%)Average CPM:6.75
uncharacterized tissueBreadth of expression: 46 out of 1739 libraries express this gene (2.65%)Average CPM:0.01
uterusBreadth of expression: 20 out of 236 libraries express this gene (8.47%)Average CPM:1.47
whole bodyBreadth of expression: 3 out of 12 libraries express this gene (25.00%)Average CPM:0.04
SAGE (18174554 tags, 331 libraries)
Tissue Breadth ? CPM ?
bloodBreadth of expression: 1 out of 1 libraries express this gene (100.00%)Average CPM:61.83
brainBreadth of expression: 30 out of 30 libraries express this gene (100.00%)Average CPM:329.51
cerebellumBreadth of expression: 1 out of 1 libraries express this gene (100.00%)Average CPM:19.50
cervixBreadth of expression: 1 out of 1 libraries express this gene (100.00%)Average CPM:263.00
colonBreadth of expression: 8 out of 8 libraries express this gene (100.00%)Average CPM:72.90
eyeBreadth of expression: 5 out of 6 libraries express this gene (83.33%)Average CPM:141.62
heartBreadth of expression: 1 out of 1 libraries express this gene (100.00%)Average CPM:284.51
kidneyBreadth of expression: 3 out of 3 libraries express this gene (100.00%)Average CPM:83.68
liverBreadth of expression: 1 out of 1 libraries express this gene (100.00%)Average CPM:6984.64
lungBreadth of expression: 1 out of 1 libraries express this gene (100.00%)Average CPM:639.42
mammary glandBreadth of expression: 14 out of 20 libraries express this gene (70.00%)Average CPM:147.65
mesothelial tissueBreadth of expression: 1 out of 1 libraries express this gene (100.00%)Average CPM:7788.29
muscleBreadth of expression: 2 out of 2 libraries express this gene (100.00%)Average CPM:55.69
nervousBreadth of expression: 1 out of 1 libraries express this gene (100.00%)Average CPM:306.74
ovaryBreadth of expression: 7 out of 10 libraries express this gene (70.00%)Average CPM:549.19
pancreasBreadth of expression: 6 out of 8 libraries express this gene (75.00%)Average CPM:207.83
prostateBreadth of expression: 10 out of 14 libraries express this gene (71.43%)Average CPM:98.74
skinBreadth of expression: 4 out of 7 libraries express this gene (57.14%)Average CPM:110.66
stomachBreadth of expression: 4 out of 4 libraries express this gene (100.00%)Average CPM:137.21
uncharacterized tissueBreadth of expression: 16 out of 20 libraries express this gene (80.00%)Average CPM:585.45
vascularBreadth of expression: 3 out of 3 libraries express this gene (100.00%)Average CPM:140.41
EvidencePolymorphism in End-Stage Renal Disease Polymorphism in Nephrotic Syndrome

Other key publications related to this gene

© 2004, KGDB, All Rights Reserved.
Department of Urology
University of California, San Francisco