Human

Human Kidney Gene DataBase
Name polymeric immunoglobulin receptor
Symbol PIGR
Aliases hepatocellular carcinoma associated protein TB6
Gene Product
  • polymeric immunoglobulin receptor
Category
UniGene Hs.205126 
Reference Sequence
mRNA: NM_002644 Protein: NP_002635
OMIM and SNP
OMIM: 173880 SNP: NCBI SNP
Locus
LocusLink: 5284Chromosome: 1Cytoband: 1q31-q41 UCSC Genome Map Eesembl Genome Map
SummaryThe poly-Ig receptor is expressed on several glandular epithelia including those of liver and breast. It mediates transcellular transport of polymeric immunoglobulin molecules. It is a member of the immunoglobulin superfamily (Hood et al., 1985 [PubMed 3917857]). The receptor has 5 units with homology to the variable (V) units of immunoglobulins and a transmembrane region, which also has some homology to certain immunoglobulin variable regions.[supplied by OMIM]
Gene Ontology
Expression
EST (460 ESTs, 142 libraries)
Tissue Breadth ? CPM ?
cartilageBreadth of expression: 2 out of 16 libraries express this gene (12.50%)Average CPM:0.41
colonBreadth of expression: 81 out of 930 libraries express this gene (8.71%)Average CPM:4.81
head and neckBreadth of expression: 4 out of 680 libraries express this gene (0.59%)Average CPM:53.68
heartBreadth of expression: 1 out of 26 libraries express this gene (3.85%)Average CPM:3.37
kidneyBreadth of expression: 2 out of 145 libraries express this gene (1.38%)Average CPM:0.96
lungBreadth of expression: 14 out of 334 libraries express this gene (4.19%)Average CPM:27.87
mammary glandBreadth of expression: 8 out of 1038 libraries express this gene (0.77%)Average CPM:24.99
muscleBreadth of expression: 1 out of 83 libraries express this gene (1.20%)Average CPM:5.28
prostateBreadth of expression: 1 out of 309 libraries express this gene (0.32%)Average CPM:0.17
stomachBreadth of expression: 11 out of 310 libraries express this gene (3.55%)Average CPM:0.61
uncharacterized tissueBreadth of expression: 9 out of 1739 libraries express this gene (0.52%)Average CPM:5.08
uterusBreadth of expression: 3 out of 236 libraries express this gene (1.27%)Average CPM:0.52
SAGE (8772739 tags, 156 libraries)
Tissue Breadth ? CPM ?
bloodBreadth of expression: 1 out of 1 libraries express this gene (100.00%)Average CPM:20.61
brainBreadth of expression: 17 out of 30 libraries express this gene (56.67%)Average CPM:32.90
cervixBreadth of expression: 1 out of 1 libraries express this gene (100.00%)Average CPM:131.50
colonBreadth of expression: 5 out of 8 libraries express this gene (62.50%)Average CPM:3000.30
eyeBreadth of expression: 3 out of 6 libraries express this gene (50.00%)Average CPM:31.37
kidneyBreadth of expression: 1 out of 3 libraries express this gene (33.33%)Average CPM:310.58
liverBreadth of expression: 1 out of 1 libraries express this gene (100.00%)Average CPM:29.91
lungBreadth of expression: 1 out of 1 libraries express this gene (100.00%)Average CPM:112.18
mammary glandBreadth of expression: 9 out of 20 libraries express this gene (45.00%)Average CPM:207.09
muscleBreadth of expression: 1 out of 2 libraries express this gene (50.00%)Average CPM:37.14
ovaryBreadth of expression: 5 out of 10 libraries express this gene (50.00%)Average CPM:49.04
pancreasBreadth of expression: 4 out of 8 libraries express this gene (50.00%)Average CPM:151.61
prostateBreadth of expression: 9 out of 14 libraries express this gene (64.29%)Average CPM:68.28
stomachBreadth of expression: 4 out of 4 libraries express this gene (100.00%)Average CPM:262.11
uncharacterized tissueBreadth of expression: 13 out of 20 libraries express this gene (65.00%)Average CPM:34.52
vascularBreadth of expression: 2 out of 3 libraries express this gene (66.67%)Average CPM:29.20
EvidencePolymorphism in Nephrotic Syndrome

Other key publications related to this gene

© 2004, KGDB, All Rights Reserved.
Department of Urology
University of California, San Francisco