| Evidence | Polymorphism in End-Stage Renal Disease
- Samuelsson O, Attman PO, Larsson R, Mulec H, Rymo L, Weiss L, Ricksten A, Samuelsson O, Attman PO, Larsson R, Mulec H, Rymo L, Weiss L, Ricksten A, Samuelsson O, Attman PO, Larsson R, Mulec H, Rymo L, Weiss L, Ricksten A Angiotensin I-converting enzyme gene polymorphism in non-diabetic renaldisease. Nephrol Dial Transplant 2000 Apr;15(4):481-6.
- Perna A, Ruggenenti P, Testa A, Spoto B, Benini R, Misefari V, Remuzzi G, Zoccali C, Perna A, Ruggenenti P, Testa A, Spoto B, Benini R, Misefari V, Remuzzi G, Zoccali C ACE genotype and ACE inhibitors induced renoprotection in chronicproteinuric nephropathies1. Kidney Int 2000 Jan;57(1):274-81.
- Osono E, Kurihara S, Hayama N, Sakurai Y, Ohwada K, Onoda N, Takeuchi M, Tomizawa T, Komaba Y, Hashimoto K, Matsunobu S, Yoneshima H, Iino Y, Osono E, Kurihara S, Hayama N, Sakurai Y, Ohwada K, Onoda N, Takeuchi M, Tomizawa T, Komaba Y, Hashimoto K, Matsunobu S, Yoneshima H, Iino Y Insertion/deletion polymorphism in intron 16 of the ACE gene and leftventricular hypertrophy in patients with end-stage renal disease. Am J Kidney Dis 1998 Nov;32(5):725-30.
- Gumprecht J, Zychma MJ, Grzeszczak W, Zukowska-Szczechowska E, Gumprecht J, Zychma MJ, Grzeszczak W, Zukowska-Szczechowska E Angiotensin I-converting enzyme gene insertion/deletion andangiotensinogen M235T polymorphisms: risk of chronic renal failure.End-Stage Renal Disease Study Group. Kidney Int 2000 Aug;58(2):513-9.
- Tomino Y, Makita Y, Shike T, Gohda T, Haneda M, Kikkawa R, Watanabe T, Baba T, Yoshida H, Tomino Y, Makita Y, Shike T, Gohda T, Haneda M, Kikkawa R, Watanabe T, Baba T, Yoshida H Relationship between polymorphism in the angiotensinogen,angiotensin-converting enzyme or angiotensin II receptor and renalprogression in Japanese NIDDM patients. Nephron 1999 Jun;82(2):139-44.
Polymorphism in HSP Nephritis
- Amoroso A, Danek G, Vatta S, Crovella S, Berrino M, Guarrera S, Fasano ME, Mazzola G, Amore A, Gianoglio B, Peruzzi L, Coppo R, Amoroso A, Danek G, Vatta S, Crovella S, Berrino M, Guarrera S, Fasano ME, Mazzola G, Amore A, Gianoglio B, Peruzzi L, Coppo R, Amoroso A, Danek G, Vatta S, Crovella S, Berrino M, Guarrera S, Fasano ME, Mazzola G, Amore A, Gianoglio B, Peruzzi L, Coppo R Polymorphisms in angiotensin-converting enzyme gene and severity of renaldisease in Henoch-Schoenlein patients. Italian Group of RenalImmunopathology. Nephrol Dial Transplant 1998 Dec;13(12):3184-8.
Polymorphism in Nephrotic Syndrome
- Syrjanen J, Huang XH, Mustonen J, Koivula T, Lehtimaki T, Pasternack A, Syrjanen J, Huang XH, Mustonen J, Koivula T, Lehtimaki T, Pasternack A Angiotensin-converting enzyme insertion/deletion polymorphism andprognosis of IgA nephropathy. Nephron 2000 Oct;86(2):115-21.
- Han SY, Kwon YJ, Jo SK, Shin JH, Cha DR, Cho WY, Pyo HJ, Kim HK ACE gene polymorphism and renal responsiveness to ACE inhibitors in IgAnephropathy patients. Korean J Intern Med 2000 Jan;15(1):13-8.
- Asano T, Tatsuma N, Yoshida J, Ohashi R, Ambo K, Tsuchiya M, Murakami M, Yamanaka N, Honda M, Yamamoto M Association of angiotensin-converting enzyme gene polymorphism and renalpathology in Japanese children with IgA nephropathy. Clin Nephrol 1999 Jun;51(6):335-40.
- Chen X, Liu S, Ye Y, Xu Q, Chen X, Liu S, Ye Y, Xu Q Association of angiotensin-converting enzyme gene insertion/deletionpolymorphism with the clinico-pathological manifestations inimmunoglobulin A nephropathy patients. Chin Med J (Engl) 1997 Jul;110(7):526-9.
- Tanaka R, Iijima K, Murakami R, Koide M, Nakamura H, Yoshikawa N, Tanaka R, Iijima K, Murakami R, Koide M, Nakamura H, Yoshikawa N ACE gene polymorphism in childhood IgA nephropathy: association withclinicopathologic findings. Am J Kidney Dis 1998 May;31(5):774-9.
- Pei Y, Scholey J, Thai K, Suzuki M, Cattran D, Pei Y, Scholey J, Thai K, Suzuki M, Cattran D Association of angiotensinogen gene T235 variant with progression ofimmunoglobin A nephropathy in Caucasian patients. J Clin Invest 1997 Aug 15;100(4):814-20.
- Yoshida H, Mitarai T, Kawamura T, Kitajima T, Miyazaki Y, Nagasawa R, Kawaguchi Y, Kubo H, Ichikawa I, Sakai O, Yoshida H, Mitarai T, Kawamura T, Kitajima T, Miyazaki Y, Nagasawa R, Kawaguchi Y, Kubo H, Ichikawa I, Sakai O Role of the deletion of polymorphism of the angiotensin converting enzymegene in the progression and therapeutic responsiveness of IgA nephropathy. J Clin Invest 1995 Nov;96(5):2162-9.
- Yorioka T, Suehiro T, Yasuoka N, Hashimoto K, Kawada M, Yorioka T, Suehiro T, Yasuoka N, Hashimoto K, Kawada M Polymorphism of the angiotensin converting enzyme gene and clinicalaspects of IgA nephropathy. Clin Nephrol 1995 Aug;44(2):80-5.
- Harden PN, Geddes C, Rowe PA, McIlroy JH, Boulton-Jones M, Rodger RS, Junor BJ, Briggs JD, Connell JM, Jardine AG, Harden PN, Geddes C, Rowe PA, McIlroy JH, Boulton-Jones M, Rodger RS, Junor BJ, Briggs JD, Connell JM, Jardine AG Polymorphisms in angiotensin-converting-enzyme gene and progression of IgAnephropathy. Lancet 1995 Jun 17;345(8964):1540-2.
- Stratta P, Canavese C, Ciccone G, Barolo S, Dall'Omo AM, Fasano ME, Mazzola G, Berutti S, Fop F, Curtoni ES, Piccoli G, Stratta P, Canavese C, Ciccone G, Barolo S, Dall'Omo AM, Fasano ME, Mazzola G, Berutti S, Fop F, Curtoni ES, Piccoli G Angiotensin I-converting enzyme genotype significantly affects progressionof IgA glomerulonephritis in an italian population. Am J Kidney Dis 1999 Jun;33(6):1071-9.
Polymorphism in Lupus Nephritis
- Akai Y, Sato H, Iwano M, Kurumatani N, Kurioka H, Kubo A, Yamaguchi T, Shiiki H, Fujimoto T, Dohi K, Akai Y, Sato H, Iwano M, Kurumatani N, Kurioka H, Kubo A, Yamaguchi T, Shiiki H, Fujimoto T, Dohi K Association of an insertion polymorphism of angiotensin-converting enzymegene with the activity of lupus nephritis. Clin Nephrol 1999 Mar;51(3):141-6.
- Prkacin I, Novak B, Sertic J, Mrzljak A, Prkacin I, Novak B, Sertic J, Mrzljak A Angiotensin-converting enzyme gene polymorphism in patients with systemiclupus. Acta Med Croatica 2001;55(2):73-6.
Polymorphism in Abnormal Kidney Development
- Hohenfellner K, Wingen AM, Nauroth O, Wuhl E, Mehls O, Schaefer F, Hohenfellner K, Wingen AM, Nauroth O, Wuhl E, Mehls O, Schaefer F Impact of ACE I/D gene polymorphism on congenital renal malformations. Pediatr Nephrol 2001 Apr;16(4):356-61.
- Hohenfellner K, Hunley TE, Brezinska R, Brodhag P, Shyr Y, Brenner W, Habermehl P, Kon V ACE I/D gene polymorphism predicts renal damage in congenital uropathies. Pediatr Nephrol 1999 Aug;13(6):514-8.
- al-Eisa A, Haider MZ, Srivastva BS, al-Eisa A, Haider MZ, Srivastva BS Angiotensin-converting enzyme gene insertion/deletion polymorphism andrenal damage in childhood uropathies. Pediatr Int 2000 Aug;42(4):348-53.
Polymorphism in Kidney Neoplasms
- Usmani BA, Janeczko M, Shen R, Mazumdar M, Papandreou CN, Nanus DM, Usmani BA, Janeczko M, Shen R, Mazumdar M, Papandreou CN, Nanus DM Analysis of the insertion/deletion polymorphism of the human angiotensinconverting enzyme (ACE) gene in patients with renal cancer. Br J Cancer 2000 Feb;82(3):550-2.
Polymorphism in Other
- Teranishi M, Ono H, Ishimitsu T, Matsuoka H, Teranishi M, Ono H, Ishimitsu T, Matsuoka H Insertion/deletion angiotensin converting enzyme gene polymorphism affectsthe microvascular structure of the kidney in patients with nondiabeticrenal disease. J Hypertens 1999 Mar;17(3):351-6.
- McLaughlin KJ, Harden PN, Ueda S, Boulton-Jones JM, Connell JM, Jardine AG, McLaughlin KJ, Harden PN, Ueda S, Boulton-Jones JM, Connell JM, Jardine AG The role of genetic polymorphisms of angiotensin-converting enzyme in theprogression of renal diseases. Hypertension 1996 Nov;28(5):912-5.
Polymorphism in Kidney Cystic Disease
- Konoshita T, Miyagi K, Onoe T, Katano K, Mutoh H, Nomura H, Koni I, Miyamori I, Mabuchi H, Konoshita T, Miyagi K, Onoe T, Katano K, Mutoh H, Nomura H, Koni I, Miyamori I, Mabuchi H Effect of ACE gene polymorphism on age at renal death in polycystic kidneydisease in Japan. Am J Kidney Dis 2001 Jan;37(1):113-118.
- Perez-Oller L, Torra R, Badenas C, Mila M, Darnell A, Perez-Oller L, Torra R, Badenas C, Mila M, Darnell A Influence of the ACE gene polymorphism in the progression of renal failurein autosomal dominant polycystic kidney disease. Am J Kidney Dis 1999 Aug;34(2):273-8.
Polymorphism in Reflux Nephropathy
- Ozen S, Alikasifoglu M, Saatci U, Bakkaloglu A, Besbas N, Kara N, Kocak H, Erbas B, Unsal I, Tuncbilek E, Ozen S, Alikasifoglu M, Saatci U, Bakkaloglu A, Besbas N, Kara N, Kocak H, Erbas B, Unsal I, Tuncbilek E Implications of certain genetic polymorphisms in scarring invesicoureteric reflux: importance of ACE polymorphism. Am J Kidney Dis 1999 Jul;34(1):140-5.
Polymorphism in Nephrosclerosis
- Lee DY, Kim W, Kang SK, Koh GY, Park SK, Lee DY, Kim W, Kang SK, Koh GY, Park SK Angiotensin-converting enzyme gene polymorphism in patients withminimal-change nephrotic syndrome and focal segmental glomerulosclerosis. Nephron 1997;77(4):471-3.
- Mallamaci F, Zuccala A, Zoccali C, Testa A, Gaggi R, Spoto B, Martorano C, Curatola A, Misefari V, Cuzzola F, Romeo G, Zucchelli P, Mallamaci F, Zuccala A, Zoccali C, Testa A, Gaggi R, Spoto B, Martorano C, Curatola A, Misefari V, Cuzzola F, Romeo G, Zucchelli P The deletion polymorphism of the angiotensin-converting enzyme isassociated with nephroangiosclerosis. Am J Hypertens 2000 Apr;13(4 Pt 1):433-7.
Other key publications related to this gene
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