Human

Human Kidney Gene DataBase
Name FK506 binding protein 6, 36kDa
Symbol FKBP6
Aliases FKBP36; PPIase; rotamase; immunophilin FKBP36; FK506 binding protein 6 (36kD); peptidylprolyl cis-trans isomerase
Gene Product
  • FK506-binding protein 6
Category
UniGene Hs.150490  Hs.511012 
Reference Sequence
mRNA: NM_003602 Protein: NP_003593
OMIM and SNP
OMIM: 604839 SNP: NCBI SNP
Locus
LocusLink: 8468Chromosome: 7Cytoband: 7q11.23 UCSC Genome Map Eesembl Genome Map
SummaryThe protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. This gene is found to be deleted in Williams syndrome.
Gene Ontology
Expression
EST (14 ESTs, 8 libraries)
Tissue Breadth ? CPM ?
brainBreadth of expression: 2 out of 759 libraries express this gene (0.26%)Average CPM:21.97
germ cellBreadth of expression: 1 out of 6 libraries express this gene (16.67%)Average CPM:1.98
testisBreadth of expression: 2 out of 180 libraries express this gene (1.11%)Average CPM:11.23
uncharacterized tissueBreadth of expression: 3 out of 1739 libraries express this gene (0.17%)Average CPM:8.31
SAGE (10618232 tags, 204 libraries)
Tissue Breadth ? CPM ?
bloodBreadth of expression: 1 out of 1 libraries express this gene (100.00%)Average CPM:20.61
brainBreadth of expression: 28 out of 30 libraries express this gene (93.33%)Average CPM:92.21
cerebellumBreadth of expression: 1 out of 1 libraries express this gene (100.00%)Average CPM:58.50
cervixBreadth of expression: 1 out of 1 libraries express this gene (100.00%)Average CPM:98.63
colonBreadth of expression: 8 out of 8 libraries express this gene (100.00%)Average CPM:65.96
eyeBreadth of expression: 5 out of 6 libraries express this gene (83.33%)Average CPM:103.72
heartBreadth of expression: 1 out of 1 libraries express this gene (100.00%)Average CPM:71.13
kidneyBreadth of expression: 3 out of 3 libraries express this gene (100.00%)Average CPM:86.32
liverBreadth of expression: 1 out of 1 libraries express this gene (100.00%)Average CPM:44.87
lungBreadth of expression: 1 out of 1 libraries express this gene (100.00%)Average CPM:67.31
mammary glandBreadth of expression: 15 out of 20 libraries express this gene (75.00%)Average CPM:93.13
muscleBreadth of expression: 2 out of 2 libraries express this gene (100.00%)Average CPM:46.42
nervousBreadth of expression: 1 out of 1 libraries express this gene (100.00%)Average CPM:90.22
ovaryBreadth of expression: 8 out of 10 libraries express this gene (80.00%)Average CPM:72.06
pancreasBreadth of expression: 6 out of 8 libraries express this gene (75.00%)Average CPM:72.74
prostateBreadth of expression: 13 out of 14 libraries express this gene (92.86%)Average CPM:114.77
skinBreadth of expression: 3 out of 7 libraries express this gene (42.86%)Average CPM:138.06
stomachBreadth of expression: 4 out of 4 libraries express this gene (100.00%)Average CPM:120.13
uncharacterized tissueBreadth of expression: 18 out of 20 libraries express this gene (90.00%)Average CPM:82.43
vascularBreadth of expression: 2 out of 3 libraries express this gene (66.67%)Average CPM:80.37
EvidenceDeletion in System Syndrom with Kidney Involvment

Other key publications related to this gene

© 2004, KGDB, All Rights Reserved.
Department of Urology
University of California, San Francisco