Human

Human Kidney Gene DataBase
Name estrogen receptor 1
Symbol ESR1
Aliases ER; ESR; Era; ESRA; NR3A1; estrogen receptor 1 (alpha)
Gene Product
  • estrogen receptor 1
Category
UniGene Hs.1657 
Reference Sequence
mRNA: NM_000125 Protein: NP_000116
OMIM and SNP
OMIM: 133430 SNP: NCBI SNP
Locus
LocusLink: 2099Chromosome: 6Cytoband: 6q25.1 UCSC Genome Map Eesembl Genome Map
SummaryThe estrogen receptor (ESR) is a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. Alternative splicing results in several ESR1 mRNA transcripts, which differ primarily in their 5-prime untranslated regions. The translated receptors show less variability.[supplied by OMIM]
Gene Ontology
Expression
EST (88 ESTs, 37 libraries)
Tissue Breadth ? CPM ?
brainBreadth of expression: 1 out of 759 libraries express this gene (0.13%)Average CPM:3.30
cartilageBreadth of expression: 1 out of 16 libraries express this gene (6.25%)Average CPM:2.58
heartBreadth of expression: 2 out of 26 libraries express this gene (7.69%)Average CPM:0.31
kidneyBreadth of expression: 1 out of 145 libraries express this gene (0.69%)Average CPM:0.59
lungBreadth of expression: 2 out of 334 libraries express this gene (0.60%)Average CPM:29.06
lymph nodeBreadth of expression: 1 out of 22 libraries express this gene (4.55%)Average CPM:0.26
mammary glandBreadth of expression: 4 out of 1038 libraries express this gene (0.39%)Average CPM:214.41
muscleBreadth of expression: 1 out of 83 libraries express this gene (1.20%)Average CPM:7.44
ovaryBreadth of expression: 4 out of 170 libraries express this gene (2.35%)Average CPM:4.52
pancreasBreadth of expression: 1 out of 20 libraries express this gene (5.00%)Average CPM:0.52
prostateBreadth of expression: 1 out of 309 libraries express this gene (0.32%)Average CPM:2.62
testisBreadth of expression: 2 out of 180 libraries express this gene (1.11%)Average CPM:3.55
uncharacterized tissueBreadth of expression: 6 out of 1739 libraries express this gene (0.35%)Average CPM:5.80
uterusBreadth of expression: 9 out of 236 libraries express this gene (3.81%)Average CPM:31.80
whole bodyBreadth of expression: 1 out of 12 libraries express this gene (8.33%)Average CPM:20.85
SAGE (2829187 tags, 55 libraries)
Tissue Breadth ? CPM ?
brainBreadth of expression: 9 out of 30 libraries express this gene (30.00%)Average CPM:18.49
cervixBreadth of expression: 1 out of 1 libraries express this gene (100.00%)Average CPM:230.13
colonBreadth of expression: 4 out of 8 libraries express this gene (50.00%)Average CPM:39.98
eyeBreadth of expression: 2 out of 6 libraries express this gene (33.33%)Average CPM:14.20
heartBreadth of expression: 1 out of 1 libraries express this gene (100.00%)Average CPM:11.85
mammary glandBreadth of expression: 8 out of 20 libraries express this gene (40.00%)Average CPM:71.94
muscleBreadth of expression: 1 out of 2 libraries express this gene (50.00%)Average CPM:18.56
ovaryBreadth of expression: 4 out of 10 libraries express this gene (40.00%)Average CPM:161.23
pancreasBreadth of expression: 1 out of 8 libraries express this gene (12.50%)Average CPM:31.03
prostateBreadth of expression: 5 out of 14 libraries express this gene (35.71%)Average CPM:22.34
skinBreadth of expression: 2 out of 7 libraries express this gene (28.57%)Average CPM:71.98
stomachBreadth of expression: 2 out of 4 libraries express this gene (50.00%)Average CPM:27.56
uncharacterized tissueBreadth of expression: 7 out of 20 libraries express this gene (35.00%)Average CPM:67.89
vascularBreadth of expression: 1 out of 3 libraries express this gene (33.33%)Average CPM:19.02
EvidencePolymorphism in Kidney Neoplasms Polymorphism in Lupus Nephritis

Other key publications related to this gene

© 2004, KGDB, All Rights Reserved.
Department of Urology
University of California, San Francisco